2024 Rome, Italy

I-01 Nurul Azrin Abd Rahman
A population pharmacokinetic/pharmacodynamic (PK/PD) model of the investigational antimalarial drug Artefenomel in a Plasmodium vivax Volunteer-Infection Study
Wednesday 09:50-11:15
I-02 Mahmoud Abdelwahab
Clofazimine population pharmacokinetics in South African patients with drug resistant tuberculosis
Wednesday 09:50-11:15
I-06 Ahmed Aliyu Abulfathi
External validation of a para-aminosalicylic acid population pharmacokinetics model using the ncappc R package
Wednesday 09:50-11:15
I-11 Marie Alexandre
Modeling viral rebound in HIV therapeutic vaccine studies
Wednesday 09:50-11:15
I-15 Vincent Aranzana-Climent
Use of a semi-mechanistic PK-PD model to quantify the combination effect of polymyxin B and minocycline against polymyxin-resistant Acinetobacter baumannii
Wednesday 09:50-11:15
I-23 Rami Ayoun Alsoud
Simultaneous Assessment of Time-to-positivity and Colony-forming Unit in tuberculosis patients under high-dose rifampicin therapy
Wednesday 09:50-11:15
I-56 David Busse
Analysis of target-site distribution of meropenem in morbidly obese and non-obese patients using nonlinear mixed-effects modelling
Wednesday 09:50-11:15
I-58 Unai Caballero
Pharmacodynamic modelling to evaluate the in vitro activity of amphotericin B against Candida auris
Wednesday 09:50-11:15
I-70 Alexia Chauzy
Semi-mechanistic pharmacodynamics modeling of aztreonam-avibactam combination to understand its antimicrobial activity against multidrug-resistant Gram-negative bacteria
Wednesday 09:50-11:15
I-72 Lu Chen
Bioavailability and the Variability of Posaconazole Exposure in Healthy Volunteers Using a Population Pharmacokinetic Analysis
Wednesday 09:50-11:15
I-73 Maxwell Chirehwa
Population pharmacokinetics of cycloserine dosed as terizidone in drug-resistant tuberculosis patients
Wednesday 09:50-11:15
I-75 Palang Chotsiri
Mechanistic modelling of primaquine pharmacokinetics, gametocyte clearance, and mosquito infectivity
Wednesday 09:50-11:15
I-78 Perrine Courlet
Influence of drug-drug interactions on population pharmacokinetics of atorvastatin and its active metabolite ortho-OH-atorvastatin in people living with HIV.
Wednesday 09:50-11:15
II-10 Donghwan Lee
Effect of Pharmacokinetic Model Misspecification on Antibiotic Probability of Target Attainment Predicted by Monte Carlo Simulation
Wednesday 15:10-16:40
II-21 Feiyan Liu
Modeling inflammatory biomarker dynamics during clinical challenge studies with lipopolysaccharide
Wednesday 15:10-16:40
II-67 Taniya Paiboonvong
Development of physiologically based pharmacokinetic model of sitafloxacin in plasma and epithelial lining fluid
Wednesday 15:10-16:40
II-68 Semra Palic
Neopterin dynamics in pediatric patients after miltefosine treatment of visceral leishmaniasis
Wednesday 15:10-16:40
II-81 Mélanie Prague
In Silico Clinical Trials for Evaluation of HIV Short-Cycle strategies
Wednesday 15:10-16:40
II-85 Chetan Rathi
Model-Informed selection of doses and sample size for a Phase 2a POC study of GSK3640254, a next generation HIV-1 maturation inhibitor
Wednesday 15:10-16:40
III-04 Christer Rimmler
Evaluating the Influence of Cardiopulmonary Bypass on the Pharmacokinetics of Cefuroxime using PBPK and PopPK Models
Thursday 09:55-11:20
III-05 Viktor Rognĺs
Bounded Integer approach to model time-varying SOFA scores from patients with carbapenem resistant infections
Thursday 09:55-11:20
III-06 Federico Romano
Predictive performance of a parasite growth dynamics model for the evaluation of anti-malarial drugs: a case study with mefloquine
Thursday 09:55-11:20
III-26 Tomás Sou
Translational PK and PKPD modelling for the analysis of preclinical in-vitro and in-vivo studies to predict efficacious human dose of apramycin
Thursday 09:55-11:20
III-29 Gabriel Stillemans
Simultaneous population pharmacokinetic modeling of darunavir and cobicistat in a cohort of HIV patients
Thursday 09:55-11:20
III-31 Herbert Struemper
Population Pharmacokinetics of Belimumab Administered Intravenously in Children with Systemic Lupus Erythematosus
Thursday 09:55-11:20
III-34 Jesper Sundell
Pharmacokinetic variability of isoniazid, and its two major metabolites in patients co-infected with tuberculosis and HIV
Thursday 09:55-11:20
III-35 Budi Octasari Susanto
Translational Model-Informed Selection of Tuberculosis Drug Combination Regimens for Early Clinical Development
Thursday 09:55-11:20
III-38 Lénaďg Tanneau
Evaluating potential link between liver enzyme abnormalities and bedaquiline exposure in multi-drug resistant tuberculosis patients
Thursday 09:55-11:20
III-39 Joel Tarning
Severe acute malnutrition results in lower exposure in children treated with artemether-lumefantrine for uncomplicated malaria
Thursday 09:55-11:20
III-42 Anders Thorsted
Model-based translation from piglets to healthy volunteers: Prediction of TNF-α and IL-6 time-courses in human endotoxin challenge studies
Thursday 09:55-11:20
III-43 Tjokosela Tikiso
A pooled analysis of abacavir pharmacokinetics in HIV-infected African children: the effect of age, malnutrition, and common concomitant co-medications.
Thursday 09:55-11:20
III-48 Sami Ullah
Population pharmacokinetics of cefepime in critically ill patients with and without impaired renal function
Thursday 09:55-11:20
III-53 Stijn van Beek
Population Pharmacokinetics and Model-Informed Precision Dosing of Isoniazid in Tuberculosis Patients
Thursday 09:55-11:20
III-58 Rob van Wijk
Nanoscale pharmacokinetics and pharmacodynamics of isoniazid treatment of tuberculosis in zebrafish larvae
Thursday 09:55-11:20
III-61 Luka Verrest
Exploring variability in paromomycin pharmacokinetics in East African visceral leishmaniasis patients
Thursday 09:55-11:20
III-65 Wenyi Wang
Physiological Response to Endotoxin Infusion in the Piglet: Modelling of changes in hemodynamic outcomes
Thursday 09:55-11:20
III-67 Zhigang Wang
A Pharmacokinetic-Pharmacodynamic model built on in vitro data predict the antibacterial effect of polymyxin B against Klebsiella pneumoniae in vivo
Thursday 09:55-11:20
III-71 Ferdinand Weinelt
A joint pharmacokinetic model of piperacillin/tazobactam including mechanistic renal clearance in critically ill patients
Thursday 09:55-11:20
III-73 Quirin Werthner
Network-based mathematical modelling of HPV transmission and cervical cancer in Germany.
Thursday 09:55-11:20
III-76 Justin Wilkins
Population Pharmacokinetics analysis of M5717, a novel antimalarial agent
Thursday 09:55-11:20
III-80 Xia Li
A Physiologically-Based Pharmacokinetic Model of Voriconazole
Thursday 09:55-11:20
III-81 Rujia Xie
Pharmacokinetic-Pharmacodynamic Analysis of Anidulafungin in Pediatric and Adult Patients with Invasive Fungal Infections
Thursday 09:55-11:20
III-84 Jinqiu Yin
Pharmacokinetic-pharmacodynamic modeling of colistin against Pseudomonas aeruginosa-associated biofilm infections
Thursday 09:55-11:20
III-88 Chenyan Zhao
Colistin to overcome resistance to ciprofloxacin - Quantifying combined effects of colistin and ciprofloxacin against four E. coli strains with different ciprofloxacin susceptibility in an in silico PKPD model
Thursday 09:55-11:20
IV-12 Alan Faraj
Drug effect of clofazimine on persisting mycobacteria explain an unexpected increase in bacterial load from patients
Thursday 15:25-16:50
IV-18 Jose Francis
A semi-mechanistic model to characterise the influence of nevirapine- and lopinavir/ritonavir-based therapy on artemether and dihydroartemisinin exposure
Thursday 15:25-16:50
IV-20 Aline Fuchs
Assessment of translation of PKPD relationship from animal to human for malaria compounds
Thursday 15:25-16:50
IV-25 Kamunkhwala Gausi
Pharmacokinetics of isoniazid preventative therapy among HIV-infected pregnant women in high tuberculosis incidence settings
Thursday 15:25-16:50
IV-38 Jinju Guk
Modelling the dose-effect relationship between DAV132, an activated charcoal based product, and fecal concentration of moxifloxacin in healthy volunteers
Thursday 15:25-16:50
IV-41 Felix Hammann
Population pharmacokinetics and generation of dosing nomograms of daptomycin at a Swiss university hospital
Thursday 15:25-16:50
IV-51 Richard Höglund
Multidrug-resistant genotypes are associated with therapeutic failure of antimalarial therapy in Cambodia; a pharmacometric approach
Thursday 15:25-16:50
IV-58 Luis Ilia
Quantitative comparison of in vitro and in vivo variability of microdialysis experiments using nonlinear mixed-effects modelling on the example of linezolid
Thursday 15:25-16:50
IV-59 Khalid Iqbal
Modelling tissue pharmacokinetics: A comparison of empiric and mechanistic PBPK modelling approaches of different complexity exemplified with moxifloxacin
Thursday 15:25-16:50
IV-61 Kris Oliver Jalusic
Pharmacokinetics of vancomycin in the cerebrospinal fluid in critically ill patients
Thursday 15:25-16:50
IV-65 Mats Jirstrand
A challenge model of TNFα turnover with LPS provocations and drug intervention
Thursday 15:25-16:50
IV-78 Aida Kawuma
Dolutegravir pharmacokinetics in co-administration with rifampicin.
Thursday 15:25-16:50
IV-84 Dohyun Kim
Optimization of dosing strategy for Colistin using population pharmacokinetic model based on the Bayesian inference
Thursday 15:25-16:50
IV-86 Franziska Isabelle Kluwe
Model-based characterisation of nonlinear voriconazole pharmacokinetics following two different routes of administration
Thursday 15:25-16:50